![]() To balance your palate, woody notes of sandalwood, amber, and musk bring warmth and decadence, making this candle rich, fresh, and enticing. Zesty notes of lemon, crisp apple, and tart red berries are the first to brighten and please, followed by the floral softness of sweet jasmine, velvety rose, and fresh green lily of the valley (muguet). ![]() Tart, tangy, yet warm, this scent carries you on a bold olfactory journey through the Mediterranean. Vetiver, a precious resin from the vetiver root, releases a warm woody note and mingles with dry, honeyed tobacco for a decadent, comforting delectable fragrance that feels cozier than curling up in bed on a lazy weekend. Our Philosophy The smallest of details can turn a home into a personal oasis. We design and source all our products with life’s needs in mind, a modern sense of beauty, and true comfort. The warm, vanilla scent of benzoin, a balsamic resin that flows from plants from the Sytrax genus, permeates the air with soft florals before tobacco and vetiver take over. About Us Since 2015, our mission has always been to transform personal spaces into dream homes with affordable and luxurious home decor. La Jolie Muse is dedicated to thoughtful design and practical luxury, creating products for the home and garden that combines effortless style, true comfort, and lasting utility. Warm, nutty, and earthy notes of rich hazelnut and creamy oat make this truly delectable. Rennes Bronze Iron 2 tiered round Fruit Basket. Burn this candle for brighter mornings with a zen touch. 78 Products Oval Scented Candle - Fresh Apple 17.55 27.00 Oval Scented Candle - Chili & Thai Mango 22.95 27.00 Joie Scented Candle - Black Coffee 15.60 24.00 Joie Scented Candle - Lavender 15.60 24.00 Joie Scented Candle - Citronella 15.60 24.00 Quelina Scented Candle - Spearmint & Eucalyptus 14.45 17. Like cloudless skies and tropical sunsets, this scent promises sunny feelings but stays down to earth with a gentle floral touch of rose, jasmine, and marine. Sparkling grapefruit, juicy melon, crisp apple, and tangy pineapple come together for a toothsome scent that's both zesty, sweet, and invigorating. Gooseberry Intimates & Swimwear bring you effortlessly sexy lingerie & swimwear to make you feel gorgeous from day time to date night. A cheerful tropical scent that's as sweet and refreshing as a summer sorbet.
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![]() PCR is a commonly used method to amplify DNA of interest in many fields such as biomedical research, diagnostic testing and forensic testing. Primer-BLAST offers flexible options to adjust the specificity threshold and other primer properties. We describe a robust and fully implemented general purpose primer design tool that designs target-specific PCR primers. Primer-BLAST also supports placing primers based on exon/intron locations and excluding single nucleotide polymorphism (SNP) sites in primers. Primer-BLAST allows users to design new target-specific primers in one step as well as to check the specificity of pre-existing primers. This tool combines BLAST with a global alignment algorithm to ensure a full primer-target alignment and is sensitive enough to detect targets that have a significant number of mismatches to primers. We present a new software tool called Primer-BLAST to alleviate the difficulty in designing target-specific primers. Furthermore, although the BLAST program has been widely used for primer target detection, it is in fact not an ideal tool for this purpose as BLAST is a local alignment algorithm and does not necessarily return complete match information over the entire primer range. The complexity of such analysis usually makes this a time-consuming and very difficult task for users, especially when the primers have a large number of hits. However, the latter is not an easy process as one needs to examine many details between primers and targets, such as the number and the positions of matched bases, the primer orientations and distance between forward and reverse primers. First, the primers flanking regions of interest are generated either manually or using software tools then they are searched against an appropriate nucleotide sequence database using tools such as BLAST to examine the potential targets. The process of designing specific primers typically involves two stages. Specific amplification of the intended target requires that primers do not have matches to other targets in certain orientations and within certain distances that allow undesired amplification. Not for Use in Diagnostic Procedures.Choosing appropriate primers is probably the single most important factor affecting the polymerase chain reaction (PCR). If you are using the primers for a PCR reaction to be used in Invitrogen TOPO cloning, the primers should not have a phosphate modification.įor Research Use Only.If you are using the primers for mutagenesis, try to have the mismatched bases towards the middle of the primer.If you are using the primers for cloning, we recommend cartridge purification as a minimum level of purification.These circumstances can lead to self-dimers or primer-dimers instead of annealing to the desired DNA sequences. Avoid intra-primer homology (more than 3 bases that complement within the primer) or inter-primer homology (forward and reverse primers having complementary sequences).Try to avoid runs of 4 or more of one base, or dinucleotide repeats (for example, ACCCC or ATATATAT).Try to avoid regions of secondary structure and have a balanced distribution of GC-rich and AT-rich domains.Typically, 3 to 4 nucleotides are added 5 ’of the restriction enzyme site in the primer to allow for efficient cutting.If the Tm of your primer is very low, try to find a sequence with more GC content, or extend the length of the primer a little. The bases also impact the Tm, G and C result in higher melting temperatures than A and T. Because the Tm is dependent on the length, it’s important to keep primers on the shorter end. Try to make the melting temperature (Tm) of the primers between 65☌ and 75☌, and within 5☌ of each other.The shorter the primers are, the more efficiently they will bind or anneal to the target. Specificity usually is dependent on length and annealing temperature. A good length for PCR primers is generally around 18-30 bases.Be mindful not to have too many repeating G or C bases, as this can cause primer-dimer formation. The G and C bases have stronger hydrogen bonding and help with the stability of the primer. Aim for the GC content to be between 40 and 60% with the 3’ of a primer ending in G or C to promote binding.Here are some guidelines for designing your PCR primers: In order to achieve successful DNA amplification, it’s important to start off with the right primer. Designing oligonucleotides and making sure that you have the right parameters for your oligo is an important step in securing results, especially in PCR Primer Design. You don’t need to worry about other settings, as AVCWare Ringtone Maker will automatically adjust them to help ensure your ringtone is of high-quality. Itunes For Iphone 4 free download - Xilisoft iPhone Transfer, Xilisoft iPhone Ringtone Maker. ![]() After you download, install, and launch the program, select an audio or video file you would like to convert.Įnter the file either by browsing your computer files or dragging and dropping it into the button in the lower right corner. Key features include drag and drop, fade-in or fade-out options, the ability to rename the ringtone and adjust the sound bite length, even after clipped.Ĭreating ringtones using AVCWare Ringtone Maker is quick and uncomplicated. How to use AVCWare Ringtone MakerĪVCWare Ringtone Maker is a free desktop tool that converts many audio and video files to WAV, AMR, MP3, M4R, M4A, and ringtone formats fully supported by most Android and iPhone models. Curious about how to use this tool to create cool ringtones? Here’s the scoop. However, you won’t have to worry about these issues when using the helpful desktop tool we’ve found. You will find no scarcity in ringtone making apps, many of which can be complicated to use, are limited in file formats, or produce poor quality sound bites. User-friendly video conversion software for. With names like Circuit, Presto and Radar, is it any wonder why many people find stock ringtones to be mediocre at best? Fortunately, there are simple programs for converting audio files to ringtones you will enjoy hearing. iRinger also includes a bunch of special effects to add to your ringtones. It’s somewhat perplexing how developers design apps that can tackle a world of tasks but continue to fail at crafting slick audio files. If you want to change something, click “Back to edit”.Do you have a love-hate relationship with your smartphone? You appreciate how it helps manage and organize many facets of your life, yet, a few features, like subpar ringtones, cause you to cringe. Listen to the sample in the player and save it to your personal device or cloud storage. The free iPhone Ringtone Maker lets you change the output format or keep the initial one. Tick the “Crossfade” box to make the transition less noticeable. Delete the selected snippet, so the rest of the audio will be merged.Tick the “Fade in” and “Fade out” boxes if you want the sound to increase and decrease gradually. Extract the selected snippet that will become your new ringtone.Trim the audio by using the sliders or setting the timing manually. Clideo will extract the audio out of the video and you will be able to cut it then. Alternatively, upload it from your Dropbox or Google Drive accounts. If you already have a music track on your personal device, click the big blue button and select it. ![]() Drag to where you want the song to start and end. ![]() Next, Ringtone Maker will show your track and time indicators. You begin by dragging and dropping an MP3 into the window. Using the app is a pleasure for the most part. Read on to learn how to use the Ringtone Maker for iPhone by Clideo. You can create your ringtone within seconds if you can click quickly enough. It’s compatible with all operating systems, be it macOS, Windows, iOS, or Android. Create your own software download - Free Ringtone Maker (Portable) 2. The iPhone ringtone creator works online, so you don’t have to download and install it wasting the precious memory of your device. Now you can turn any melody you like into a track for your smartphone completely for free. Gone are the days when you had to purchase ringtones and the choice was quite limited. Looking for the best ringtone maker for iPhone? Have a close look at the one by Clideo! ![]() Accurate text recognition: The best scanning apps use optical character recognition (OCR) to locate text in an image and convert it to an editable document.Different apps provide different scan resolutions and different filters, some of which are better than others at smoothing out wrinkles, shadows, and other blemishes. Great image quality: Although the scan quality is partly dependent on the quality of your phone’s camera, it also has a lot to do with the app itself.We looked for apps with intuitive controls, a thoughtful layout, and helpful features such as automatic document recognition and capture. Ease of use: Above all else, scanning apps need to be easy to use, or else you won’t want anything to do with them.・ Connect your iPhone/iPad with a desktop for transferring files using USB or WiFi connection. ・ Store and secure files on iCloud Drive, Dropbox, OneDrive, Google Drive, Evernote, Box, FTP, WebDav, etc.īackup Files between iOS Devices, Mac and PC ・ Support a total of 36 voices for 26 languages. ・Make continuous scans and automatically detect edges of scanned objects. ・ Encrypt to protect your PDF files from unauthorized reading with a password. ・ Passcode to prevent unauthorized use of PDF Reader Pro. PROTECT CONTENT WITH PASSWORD AND ENCRYPTION OCR pdfs to convert scanned PDF files or pictures into editable and searchable PDFs or TXT files.・ Compress large PDFs to reduce file size. ・ Create a new PDF as a blank PDF or from your clipboard content. ・ Convert MS Office documents, iWorks, web content, and images to PDFs. Export from PDF to Microsoft Word (.docx), PowerPoint (.pptx), Excel (.xlsx), RTF, Text, Image, HTML, CSV, and more Offline.・ Fill out any PDF forms with interactive fields such as text fields, checkboxes, radio buttons, combo boxes, list boxes, etc. ・ Work with static PDF forms created in Adobe Acrobat. ・ Rotate, rearrange, add, and delete PDF pages. ・ Insert blank pages / another PDF to import specified content. ・ Extract the desired pages to create a new PDF. ・ Merge & Split PDFs available, split documents into multiple documents or combine multiple pages into a new one. ・Create a Flattened copy to flatten PDF to make the contents static. ・Add and edit watermarks to keep your PDFs safe and professional. Easily resize or move images for a better layout. ・Modify PDF images such as cropping, rotating, deleting, replacing, etc. Fast change the font color, size and style. Easily fix typos or other inaccurate content. ・ Share your annotated PDFs with others via PDF documents/Flattened copy/ Summary/ Original PDF. ・ Support to link any part of the text to a different page, email or website. ・ Insert pre-designed stamps such as Approved, Confidential and more. ・ Create multiple signatures with trackpad, keyboard or images. ・ Annotate PDFs with highlight, underline, strikethrough, note, freehand, text box, anchored note, rectangle, circle, line etc. ・ DRM, supports Vitrium* protected PDF files (Like University of Phoenix ebooks). ・ Fast files Printing to directly print PDFs from your device. ・ Easy content navigation with bookmarks/outlines. ・ Use text-to-speech feature to read selected text with no time limits. ・ Support crop mode, tabbed PDF reading, continuous page view, auto scroll and more. ・ Choose vertically/horizontally scroll pages or single pages/two pages/book mode. ・ View PDFs with various themes like night mode to comfort your eyes. PDF Reader Pro Edition for Professional is your last choice of PDF application. With support for reading files from popular productivity suites, it’s a convenient way to take the office anywhere you go. ![]() PDF Reader Pro offers even more - merge and combine multiple documents, split your PDFs, insert pages from another PDF, insert photos or hyperlinks to your PDFs, Convert PDF to Word and other Microsoft Office® formats. Import files from your computer or the cloud, then complete forms, add freehand drawings and audio notes and more. It also makes it easy to organize, annotate and edit your PDFs. PDF Reader Pro helps much for anyone who reads, edit, highlights, OCR, signs, converts, creates, protects, compresses and fills out PDFs on their iPhone and iPad. Even if you are already on a preventive course, don’t hesitate to go for another dose if you show signs of AMS. The dosage depends on your symptoms, but usually start off with 250 mg every 12 hours, or if it’s bad, then every 6 hours. Go on a curative course at the sign of any mild symptoms of AMS. Always make it a habit to carry a strip of Diamox with you if you’re going above 10,000 ft. So you don’t really have to go on a preventive course for treks that climb to just around 12,000 ft - Kedarkantha, Dayara, Deoriatal, Brahmatal.īut that does NOT mean you cannot get AMS on these easier treks. We have seen it come of use mostly above the 10,000 ft mark - both in terms of the preventive course and a curative course. ![]() It also thins your blood, making it easier for your heart to pump oxygenated blood to parts of your body. It makes you breathe faster and deeper, taking in more oxygen. We use it to prevent and also treat Acute Mountain Sickness.ĭiamox helps you by making you acclimatise faster. And I’m not surprised, because that’s how important Diamox is. The first Life Saving Drug is Diamoxĭiamox has almost become a household name amongst trekkers. Hopefully, I’ll remove any apprehensions you may have about these medicines. ![]() I’m not giving you a medical discourse on it, but I’ll share some tidbits from what we have experienced over the past 10 years of running treks in the Himalayas. Today I’ll give you some insight about these Life Saving Drugs. The three Life Saving Drugs are Diamox, Nifedipine and Dexamethasone. We have seen time and again that these medicines have come to the rescue of trekkers, even in severe cases of AMS, HAPE and HACE. In this post, I’m talking about 3 Life Saving Drugs that you must always have with you at high altitude. ![]() Causes of the Service Brake Assist Message It’s normally included with vehicles as part of a safety package, or it can be added as an optional feature. It’s an autonomous technology that handles the operation for you. If there’s a dangerous situation determined by the sensors and you aren’t braking despite warnings, the car will brake on its own. On the other hand, the Automatic Emergency Braking system is going to work without your input. If you push on the pedal but not hard enough for the situation, the advanced system is going to give you the extra boost you need. Brake Assist is going to apply pressure for you. Automatic Emergency Brakingīrake Assist might sound like a form of Automatic Emergency Braking, but these two aren’t the same. ABS also keeps the wheels from locking up, so you can come to a stop safely. On the other hand, ABS maintains the braking of the vehicle if the wheels start to lock-up. It helps drivers stop before a collision occurs. However, both systems are meant to improve braking performance.īrake Assist can supply additional pressure on the brake pedal if there’s an emergency. It’s not identical to anti-lock brakes (ABS), which are included with every vehicle these days. ABSīrake Assist is a high-tech safety system included in some modern vehicles. It can prevent an accident from occurring, which is priceless. This added pressure closes the distance until the vehicle is completely stopped. If the system determines that a fast stop is necessary, but you haven’t fully pressurized the pedal, extra hydraulic pressure will be applied. It ensures that the pressure is sufficient enough to prevent collisions during an emergency stop. The Brake Assist system measures how much pressure is applied to the brake pedal. If more pressure is needed in the event of an emergency, this advanced system supplies the additional power. Either way, it should be looked at right away.īrake assist monitors the amount of pressure being placed on the brake pedal. It’s possible that a brake sensor has failed or there isn’t enough pressure in the brake system. When the Service Brake Assist message comes on the dashboard, it means there has been a malfunction with the Brake Assist system. ![]() Is brake assist the same as ABS? What Does Service Brake Assist Message Mean? ![]() To learn the video parameters of the default MP4 conversion profiles and the approximate output file size, please have a look at the table below:Īpproximate output file size of a Standard DVD movie (1:40:00)įreemake DVD to MP4 Converter perfectly supports Windows 10. So you can easily watch the converted file on an HD screen, but the movie won't be in HD. By default, the highest resolution that the VOB video format can handle is 720x480 pixels per frame for NTSC or 720x576 pixels per frame for PAL. Due to the nature of the DVD format, the movies in it don’t exist in full high quality dimensions. Please don’t choose Full HD quality options. Name your media profile to save it for regular usage. If your device is not on the list of ready presets in Freemake DVDs Converter, you can create a custom conversion preset with adjustable video quality settings that will suit your goal best of all: video codec, frame size, bitrate, audio parameters and other geeky settings for converting your DVD videos. Each option provides a set of easy ready-to-use profiles for DVDs conversion and etc. ![]() Select a ready preset from the drop-down menu to rip DVD to MP4, AVI or MKV properly. You might also embed free subtitles downloaded from the Internet (SRT, ASS, SSA file formats) into your movie before converting DVD video files to AVI, DVD to MP4 or other popular output formats. You can preview the video before converting DVD to MP4 in Freemake video editor to check you made everything correctly. ![]() Please note that only one voice audio track and only one subtitle track are accepted by Freemake DVD to MP4 Converter. ![]() These features are available in the main window of the program. In case your DVD disc contains several movies, and you want to extract all the disc files as MP4s, select all VOB videos from the DVD folder.įor DVD movies that come with multiple audio and subtitles tracks, select one track as an audio and one track for subtitles. Choose the biggest VOB (.vob) file from the list for ripping. You may find this folder in your disc C in "My Videos". Select your DVD drive with the disc, and then a VIDEO_TS folder. In the video converter find the "+DVD" button at the top row and click it. Keep in mind that Freemake DVD Converter doesn't support & open CDs. Because both file elements are compressed, MP4s normally have a smaller file size than many other video formats, but still maintain relatively high quality for sharing online.Prerare a DVD disc you need to convert to other video format. The video part is usually compressed with MPEG-4, and the audio is usually compressed using AAC, which is the audio format associated with iTunes. MP4 videos are made up of video and audio elements that are compressed separately. MP4 is usually the preferred format for uploading videos to YouTube, Vimeo or other websites. As MP4 is a standardised format, it will normally play easily on most devices and media players, including Windows Media Player, QuickTime, and VLC. It was originally developed by the Moving Picture Experts Group (MPEG) but has become an ISO standard, meaning that it’s now maintained by the International Organisation for Standardization. MP4 was developed to be easily played and shared. MP4, sometimes called MPEG4, is one of the most common video formats. ![]() ![]() (Individuals will be able to change the briefcase to their work profile picture in Edge settings, if they'd prefer to do so.) Edge for Business also will support company branding and customization.Ĭustomers should not experience any disruption from the addition of Edge for Business, Microsoft officials claim. It also will be available on mobile the week of the 17th, but the updated icon, automatic switching, and management via the Edge management service in the Microsoft 365 admin center will be available for mobile "in the future," the spokesperson clarified.Ĭustomers will know they've been automatically transitioned to the Edge for Business mode because the updated Edge icon will include a briefcase in the lower left corner. Update (August 14): A spokesperson said Edge for Business also would come to Mac and Linux as of Edge Stable Version 116, the week of August 17. Officials also said the Edge for Business mode will be available on mobile devices at some point in the future. Additionally, the new Edge for Business mode will be coming to macOS and Linux I asked Microsoft when this would happen but have not heard back. The Edge for Business mode, which has been available in preview for the past couple of months, will be part of Edge Stable Version 116 browser release, which is scheduled to begin rolling out the week of August 17. Edge for Business will provide a separation of syncing and browser history between Edge personal and Edge work sites - something which could bring privacy and possibly security benefits to organizations that rely on the Edge browser. ![]() Those who sign into Edge using Azure Active Directory (now known as Microsoft Entra ID) will be moved automatically to this new mode, known as Microsoft Edge for Business. As of the week of August 17, Microsoft will be making a new Edge browser mode the default version of Edge for some of its business customers. ![]() Link to the template Content calendar template Google Sheets You can use this template or check out more options in our blog post, Project Status Report Template. The project calendar template will help you set up a project plan and track information such as status, work in progress, tasks completed, and much more. Link to the template Calendar Google Sheets template by purpose Project calendar Google Sheets template This template shows various sources of money in and out in a single spreadsheet. The yearly home budget calendar template lets you schedule monthly revenue and expenses, review net totals, and see how things change year-to-year. Link to the template Yearly home budget calendar template for Google SheetsĮarlier, we blogged about how to build a simple budget template in Google Sheets. It looks like a regular calendar with cells where you can put short remarks about each day of the month. You can use a monthly calendar template to schedule all kinds of plans. Calendar template in Google Sheets for different time periods Google Sheets monthly calendar template
![]() What You Should Know About Smart Switches and Dimmers What is Apple HomeKit? I lived with these products to figure out how they work on a day-to-day basis, just as you’ll be using them. I evaluated their setup processes, apps, physical and digital performance, smart home ecosystem integrations, remote control capabilities, and how well they work Siri. To adequately test these switches, I installed the switches and dimmers throughout my home and connected them to an Eero Mesh Wi-Fi router. For this guide, I spent hours with each switch, as well as plenty of time getting to know my breaker box and learning how to wire smart switches and dimmers. I’ve tested just about every smart home gadget you can imagine, but smart lighting is the category I interact with the most daily. I live in a home full of smart speakers, home security cameras, smart lights, appliances, and more connected gadgets that work with smart assistants like Alexa, Google Assistant, and Siri. Hi, I’m Rachel Murphy, Reviewed’s resident smart home expert. How We Tested HomeKit Smart Switches and Dimmers The Tester Wemo Wi-Fi Smart Dimmer Switch (second-gen) Leviton Decora Smart Wi-Fi Dimmer (second-gen)Ĥ. Leviton Decora Smart Wi-Fi (second-gen)ġ. Wemo Wi-Fi Smart Light Switch (second-gen)ĥ. These are the best smart in-wall switches and dimmers for Apple HomeKit we tested, ranked in order:Ģ. However, there are plenty of other great switches for Apple HomeKit in our guide to choose from. Is the best smart switch we’ve tested for Apple HomeKit, while the best dimmer switch is the Lutron Caséta Smart Lighting Dimmer Switch Starter Kit ( available at Amazon). After extensive testing, the Lutron Smart Switch We’ve also divided this guide into regular smart switches, and smart dimmers for your convenience. When trying to choose a smart switch or dimmer, it’s important to know that certain ones are supported by HomeKit and others are not. Rachel Murphy, smart home wizard, DIY home renovator, and mom to four.Ĭarrying in an armful of groceries late at night? Feeling lazy and don’t want to get off the couch? Thanks to smart light switches and smart dimmers for Apple HomeKit, all you have to say is “Hey Siri, turn on the lights,” (or "dim the lights") and you’ll never fumble for another switch again. Sarah Kovac, disabled editor covering adaptive products. |
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